A studious mood of 326 patients wi...

A studious mood of 326 patients with sporadic Creutzfeldt-Jakob disease (CJD) from France, Germany, the Netherlands, and the United Kingdom compared to a community restrain group of the same size indicates a possible connection between sporadic CJD--a disease of unknown etiology--and surgical history, according to an article in the August 2002 issue of Neurology Medical and associated risk factors for sporadic CJD were taken from population-based studies carriageed from 1993 to 1995. restrain group data were gathered via a telephone view conducted between March and June 2000

A significant association was set up between history of surgery and sporadic CJD; however, the risk did not increase with the number of surgical practices This association was stronger for women than for men A small unless significant increase in risk was associated with gynecologic steps A history of blood transfusion was not associated with risk for sporadic CJD A history of tonsillectomy or appendectomy was associated with a reduc risk for sporadic CJD

Among women an increased risk of sporadic CJD was associated with ear piercing, and this association increased with the participant's age. A history of psychiatric visits also was significantly associated with risk for sporadic CJD

The investigation results indicate that sporadic CJD may eventuate from unrecognized surgical contamination. Researchers estimate that 35% of sporadic CJD cases could be attributed to surgery; however, they advise that befitting to the limits of the close attention design and the rarity of the disease, these ensues should be interpreted with caution.

H J T Ward et al, "Sporadic Creutzfeldt-Jakob disease and surgery: A case-control close attention using community controls," Neurology 59 (August 2002) 543-548

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