Phase 3 comes of EXPRESS (EX...

Phase 3

comes of EXPRESS (EXpanded PRophylaxis Evaluation Surgery Study) a Phase 3 clinical trial, showed that treatment with AstraZeneca's (Wilmington, DE) investigational oral anticoagulant Exanta (ximelagatran) significantly reduc the risk of proximal astute vein thrombosis (DVT) and pulmonary embolism (PE) after orthopedic surgery compared with the low-molecular-weight heparin, enoxaparin (23% v 63%) Treatment with the studious mood drug showed a 67% risk reduction (18% v 55%) for total hip replacement and a 60% risk reduction (33% v 82%) for total knee

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