Salpingo-oophorectomy measures per...

Salpingo-oophorectomy measures performed on carriers of breast cancer (BRCA) have been institute to reduce the risk of certain protoplasts of cancers, according to couple studies published in the May 23 2002 issue of The modern England Journal of Medicine. These representations of cancers include BRCA, BRCA-related gynecologic cancer, and coelomic epithelial cancer.

The first studious mood included 170 women who were age 35 or older who had not undergone bilateral oophorectomy. They chose to either be observ for ovarian cancer or bear salpingo-oophorectomy. In the group that underwent treatment (n = 98) three women expanded breast cancer and one cause to growed peritoneal cancer. Among those who chose observation (n = 72) eight expanded breast cancer, four ovarian cancer, and individual peritoneal cancer.

Researchers in the inferior study identified 551 women with BRCA1 or BRCA2 mutations and determined their incidence of ovarian cancer. Of these, 259 women had undergone bilateral prophylactic oophorectomy, and 292 were have the direction ofs who had not undergone the course Six women who underwent the deed were diagnosed with ovarian cancer at the time of the transaction and two were diagnosed with peritoneal carcinoma at 38 and 86 years after the action In comparison, 58 women in the ascendency group were diagnosed with ovarian cancer after a mean follow-up of 88 years.

issues of these studies support the discussion of using salpingo-oophorectomy as part of a preventive oncology strategy for women with BRCA mutations. This operation can be used to aid in the detection of early-stage, curable ovarian cancer in women who have these mutations.

N D Kauff et al, "Risk-reducing solpingo-oophorectomy in women with BRCA1 or BRCA2 mutation," The novel England Journal of Medicine 346 (May 23 2002) 1609-1615

T R Rebbeck et al, "Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations," The strange England Journal of Medicine 346 (May 23 2002) 1616-1622

COPYRIGHT 2002 Association of Operating compass Nurses, Inc.

COPYRIGHT 2002 Gale Group